alexa Abstract | Visible Spectrophotometric And HPLC methods Estimation Of Suprofen From Bulk Drug Samples

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication Open Access

Abstract

One visible spectrophotometric and one HPLC method have been developed for estimation of suprofen from bulk drug sample. Developed visible spectrophotometric method is based on formation of chloroform extractable coloured complex of drug with copper (II) acetate in presence of potassium chloride and acetate buffer pH 5.8. The coloured complex shows absorbance maxima at 682.0 nm. Beer's law was obeyed in the concentration range of 0-10 mg/ml of suprofen. Developed HPLC method was a reverse phase chromatographic method using inertsil C18 column and acetonitrile:water::35:65 pH 2.7 as mobile phase with detection at 254 nm. Caffeine was used as internal standard for HPLC method. Linearity was observed in concentration range of 20-250μg/ml of suprofen. Results of analysis for both the methods were validated statistically.

To read the full article Peer-reviewed Article PDF image

Author(s): I Singhvi S C Chaturvedi

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us