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The present work describes a simple, sensitive and precise visible spectrophotometric method for the estimation of Gliclazide in bulk drug as well as in pharmaceutical dosage form. This method is based on the formation of orangered chromogen (maxat 512nm) by complexation of Gliclazidewith 1,10- phenanthroline in presence of ferric chloride. The proposed method is statistically validated and found to be useful for the routine determination of Gliclazide in tablets.
Gliclazide, Visible spectrophotometry, Tablets, Validation