alexa Abstract | An Updated Overview on Safety of Probiotics


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Abstract

It is claimed that medical remedies have been dangerous since the age of Hippocrates. Cyril Chantler has rightly stated that “Medicine used to be simple ineffective and relatively safe. Now it is complex effective and potentially dangerous”. This reflects the risk and benefits of modern drugs. There is low risk with modest benefit offered by most probiotics. There are health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. Probiotics are sometimes named as “pharmabiotics” because now days their manufacture and production have increased many folds and pharmaceutical industries are earning dollars and dollars. The sales of probiotics have gained an immense height in present pharma market. Thus Probiotic use in clinical medicine has increased tremendously. But the safety of probiotics in humans receiving nutritional support has to be understood completely. There are always chances of potential hazards of probiotic bacteria for immunodeficient patients. There is an urgent need to evaluate deficiencies in labeling of commercial probiotics. The compatibility of probiotics with cow’s milk has to be established. It is to be emphasized that various probiotics differs in respect of bioavailability, biological activity, doses and composition.so proper implementation of pharmacovigilance programmes can dramatically help to increase safety standards of probiotics.

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Author(s): Vivek Sharma, Shalini Sharma

Keywords

Accurate labeling merits and demerits pharmabiotics pharmacovigilance safety aspects, Pharmaceutics,Pharmaceutical Technology

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