Journal of Plant Biochemistry & Physiology
Open Access

Abstract

Anti-Diabetic Activity of Dracaen cinnabari Balf.f Extracts from Resin in Socotra Island-Yemen

Yasser Hussein Eissa Mohammed and Shaukath Ara Khanum

In the developing countries, the medical plants play an important role in treatment diabetes mellitus. This significant comes due to their cost effectiveness. Diabetes mellitus, a metabolic disorder is becoming a serious threat to mankind health. The herbal drugs with anti-diabetic activity are till now to be commercially formulated as modern medicines, even though they have been acclaimed for their therapeutic properties in the traditional systems of medicine. In this paper, we have reported a study based on anti-diabetic properties of Dragon cinnabari resin. The resin of plant material was collected, shade dried and extracted with different solvents using soxhlet extraction procedure. In vitro anti diabetic activity is assayed with standard glucose uptake procedure against MCF-7 cell line. From the analysis it was found that, glucose uptake inducing activity of ethyl acetate extract was found to be higher than Metformin, whereas other extracts did not display much anti diabetic activity against MCF-7 breast cancer cell line. Based on the glucose uptake studies against MCF-7 cell line, the ethyl acetate extract could be used as potential source for anti-diabetic drugs.