alexa Abstract | Bartonella Henselae Initial Infection of Mature Human Erythrocytes Observed in Real Time Using Bacterial Endogenous Fluorescence
ISSN: 2329-891X

Journal of Tropical Diseases & Public Health
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Bartonella henselae is a causative agent of anemia, cat scratch disease, bacillary angiomatosis, recurrent fever, hepatitis, endocarditis, chronic lymphadenopathy, joint and neurological disorders. B. henselae are intra-erythrocytic bacteria. The goal of this study was to visualize the B. henselae invasion into enucleated human red blood cells in real time using bacterium endogenous fluorescence. We took advantage of the unique fluorescence emission spectral profile of the bacteria. We used a linear unmixing approach to separate the fluorescence emission spectra of human erythrocytes from native B. henselae when excited at 488nm. Human blood samples were inoculated with B. henselae and incubated for 60 hours. 3-D live images were captured at select intervals using multi-photon laser scanning microscopy. Uninfected blood samples were also analyzed. This study revealed bacteria entering mature erythrocytes over a 60 hour time period.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Gislaine Vieira-Damiani, Marna Elise Ericson, Marilene Neves da Silva, Kalpna Gupta, Tania Benetti Soares, Amanda Roberta de Almeida, Vitor Bianchin Pelegati, Mariana Ozello Baratti, Carlos Lenz Cesar, Maria Letícia Cintra and Paulo Eduardo Neves Ferreira Velho

Keywords

Bartonella henselae, Anemia, Recurrent fever, Endocarditis, Lymphadenopathy, Bacteria

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords