Journal of Allergy & Therapy

Abstract

Bet v 2 Responsibility in Birch-Induced Symptoms

Metz Favre C, Pauli G, Castro L, Valenta R and de Blay F

We report the case of a patient who first had grass pollinosis associated to food allergy, especially melon, and who developed secondarily early spring pollinosis which could be related to sensitization to the birch profilin. This patient, whose birch pollinosis was confirmed by nasal provocation test, was not sensitized to Bet v 1, the major birch pollen allergen in North Western Europe. We demonstrated by inhibition studies using grass and birch profilins that the clinical birch allergy was induced by the cross reacting profilin present both in birch and grass pollen and also in melon.