alexa Abstract | Biochemical and Pharmacological Effects of Mitoxantrone and Acetyl-LCarnitine in Mice with a Solid Form of Ehrlich Tumour
ISSN: 2167-7700

Chemotherapy: Open Access
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Commentary Open Access

Abstract

Since the beginning of 1990, our Laboratories begun a series of in vivo experimental studies to evaluate the effect of carnitine derivatives on the antineoplastic activity of mitoxantrone (MX) a dihydroxyanthracene derivative on various animal models of cancer The objective was to determine pre-clinically whether carnitine and its acyl-derivatives in combination with mitoxantrone could be found to be good candidates to ameliorate host’s metabolic response to tumour processes, and therefore could play a valuable role in the field of cancer treatment.

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Author(s): Niang M*, Soukup T, Bukac J, Siman P, Stoklasová A, and Cerman J

Keywords

mitoxantrone,pre-clinically,chemotherapeutic treatments,tumour, mitoxantrone,pre-clinically,chemotherapeutic treatments,tumour

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