alexa Abstract | Chemical Composition and Antimicrobial Activity of Essential Oils Isolated from Aerial Parts of Prangos asperula Boiss. (Apiaceae) Growing Wild in Lebanon
ISSN: 2167-0412

Medicinal & Aromatic Plants
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Prangos species have been commonly used in traditional medicine in East Mediterranean and Middle Eastern countries. The hydrodistilled essential oils by HDC from different fresh aerial parts (stems and leaves, flowers and fruits) of Prangos asperula Boiss., growing wild in Lebanon were analyzed by gas chromatography-mass spectrometry. Forty two, 46 and 4 compounds representing 75.5%, 86.9% and 99.8% of the total fresh stems and leaves, flowers and fruits oils were, respectively, identified. The main compounds characterizing these oils were nerolidol (15.2%), p-menth-3-ene (13.3%), β-myrcene (9.2%) in stem and leaves; p-menth-3-ene (14.9%), nerolidol (14.7%), β-phellandrene (7.9%) in flowers; sabinene (43.5%), β-phellandrene (36.1%), α-phellandrene (11.9%) and α-terpinene (8.3%) in fruits. The antimicrobial activity of the total essential oil evaluated by growth inhibition and MIC values revealed variable levels of susceptibility in the tested bacteria and fungi. S. aureus displayed highest sensitivity (15.06 mm, MIC 5.0 μl), followed by E. coli (11.80 mm, MIC 10.0 μl), A. fumigatus (9.16 mm, MIC 10.0 μl), T. mentagrophytes (7.3 mm, MIC 25 μl), S. enteritidis (3.8 mm, MIC 25 μl) and C. albicans (1.96 mm, MIC 50 μl). The oil displayed a remarkable activity against both S. aureus being more effective than the antibiotic Norfloxacine (10 μg) and T. mentagrophytes which was completely resistant to the antifungal Nystatine (100 μg). The findings confirm the traditional use and promising potential of the antibacterial properties of this plant oil. This opens the possibility for further research on other biocidal activities and investigations of individual antimicrobial and antifungal component.

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Author(s): Mneimne M, Baydoun S, Nemer N and Apostolides NA


Prangos asperula, Essential oils, Nerolidol, Sabinene, Antimicrobial activity, Aromatic Compounds, Aromatic Crops, Aromatic Flowers

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