Research Article Open Access
The prevalence of atherosclerosis and its clinical sequele like coronary artery disease (CAD) and peripheral vascular disease (PAD) is increasing among Indians and Diabetic population is more prone for atherosclerosis than normal population. Lipid profile is one of the basic and important parameters done to screen CAD, this study was under taken to compare lipid levels between diabetic and normal population. 30 normal individuals (mean age 48.83 ± 8.58) and 30 T2DM (mean age 49.86 ± 7.21) were selected and were age and also BMI matched. Their blood samples were evaluated for FBS, PPBS, Total Cholesterol, Triglyceride,HDL cholesterol, LDL Cholesterol, VLDL Cholesterol. LDL was found to be significantly higher in T2DM than non diabetics (P = 0.035132). T – CHOL, TGL , VLDL were comparatively higher in T2DM although not significantly. HDL was comparatively lower though not significantly in DM than in normals. Despite similar BMI as that of normals,T2-DM are more prone for atherosclerosis and its clinical sequel.
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Author(s): Shashikala KT and Srinivasulu Naidu S
LDL, HDL, T2DM (Type II Diabetes Mellitus), Lipid Signaling Pathways, Type II Diabetes Mellitus