alexa Abstract | Comparison of Macrodosimetric Efficacy of Transarterial Radioembolization (TARE) by Using 90Y Microspheres of Different Density of Activity
ISSN: 2090-0902

Journal of Physical Mathematics
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Purpose: Transarterial 90Y microspheres radioembolization is emerging as a multidisciplinary promising therapeutic modality for primary and metastatic cancer in the liver. Actually two different type of microspheres are used, whose main characteristic is the different density of activity (activity per microsphere). In this paper the effect due to the possible different distribution of the microspheres in a target is presented and discussed from a macrodosimetric point of view. Material and methods: A 100 g virtual soft-tissue target region has been builded. The administered activity was chosen to have a target average absorbed dose of 100 Gy and the number of 90Y microspheres needed was calculated for two different activity-per-microsphere values (2500) Bq/microsphere and 50 Bq/microsphere, respectively). The spheres were randomly distributed in the target and the Dose Volume Histograms were obtained for both. The cells surviving fractions (SF) for four different values of the radiobiological parameter α were calculated from the Linear - Quadratic model. Results: The DVH obtained are very similar and the SF is almost equal for both the activity-per- microsphere values. Conclusions: This macrodosimetric approach shows no radiobiological difference between the glass and resin microspheres. Thus the different number of microspheres seems to have no effect when the number of spheres is big enough that the distance between the spheres in the target can be considered small compared to the range of the β-particles of 90Y.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Traino AC, Piccinno M, Boni G, Bargellini I and Bozzi E

Keywords

Microspheres, β-particles, Linear-quadratic model,TheraSphere, Physical Mathematics, Axioms, Topology, Integration , Algebraic Geometry, Quantum Mechanics, mirror symmetry, Noether's theorem, Quantumelectrodynamics, Hamilton Mechanics, vector bundle, Riemannian Geometry, Theory of Mathematical Modeling, Fourier Analysis, Theoretical Physics, Analytical Geometry, Differential Equations, Complex Analysis.

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords