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Editorial Open Access
Anatomically, intervertebral disc (IVD) consists of three part; nucleus pulposus, annulus fibrosus and cartilage end plate (CEP) at the cranial and caudal vertebral interface of the disc. In both animals and humans, the IVD consists largely of extracellular matrix with a low cell density. In many respects, that degeneration and age- related changes are characterised by biochemical and structural changes components of the IVD.
Intervertebral disc, Melatonin, Osteoblast, Spinal Canal,Spinal Diseases,Spinal arteriovenous malformations