alexa Abstract | Environmental Stressors: Is the Sperm Cell Vulnerable or Resilient?
ISSN: 2167-0250

Andrology-Open Access
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article Open Access


The sperm is a unique cell, differing from other cells in physiology and function. It survives an arduous journey through male and female reproductive tracts, to ensure that an intact male genome reaches the site of fertilization. In addition, it has also been recognized to wield epigenetic control over early embryonic development. Environmental degradation over the past years has exposed the human sperm to myriads of toxicants which have adversely affected its structure and function. In correlation, there are reports of decline in sperm counts and fertility, although there is still no concrete evidence to substantiate these claims. Moreover population statistics in most developing nations do not conform to data of declining fertility. In addition there are certain researches, in agreement with our data of normal, fertile volunteers, which also suggest no change in semen characteristics or sperm numbers over the past three decades. These findings indicate that despite the barrage from environmental agents, spermatozoa have withstood the test of time and have emerged resilient. Hence, in addition to the manifold machinery that operate to protect the spermatozoa including toll-like receptors, anti-oxidants, heat shock proteins etc., there possibly exists an in-built, genetically programmed, population specific mechanism that reinforces its nuclear integrity to protect this cell from the onslaught of toxic influences. Research in this direction is underway at our laboratory and other research centers to delve into the enigma of sperm endurance.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Highland H


Human spermatozoa, Environmental toxicants, Fertility decline, Chromatin, Genetic regulation, Resilience, Human Sperm, Azoospermia, Spermatocele, Semen Analysis

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version