700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ ReadersThis Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Case Report Open Access
Hemophagocytic lymphohistiocytosis (HLH) diagnosed in the course of acute myeloid leukemia (AML) is generally triggered by treatment-induced infections. AML-induced HLH is a very rare situation for which no diagnostic or therapeutic guidelines are available. We report the occurrence of HLH in an AML5 post-transplant relapse. In our case, the absence of detectable pathogen and the parallel evolution between HLH and leukemia burden suggested a direct link between AML and HLH. We suggest that the diagnostic of AML-related HLH should be promptly considered in front of unexplained fever, cytopenia, liver dysfunction or neurological symptoms as therapeutic intervention is urgent in this life-threatening situation.
To read the full article Peer-reviewed Article PDF
| Peer-reviewed Full Article
Author(s): Maya Belhadj, Barbara Burroni, Felipe Suarez, Frederic Pene, Nicolas Chapuis, Sylvain Pilorge, Lise Willems, Patricia Franchi, Bénédicte Deau, Didier Bouscary, Jerome Tamburini and Marielle Le Goff
AML, HLH, Acute Lymphoblastic Leukemia, Acute Megakaryocytic Leukemia, Acute Myleoid Leukemia, Leukemia