alexa Abstract | Paraneoplastic Cerebellar Degeneration: A Rare but Important Consideration
ISSN: 2165-7920

Journal of Clinical Case Reports
Open Access

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Case Report Open Access

Abstract

Paraneoplastic cerebellar degeneration is an uncommon autoimmune disorder characterized clinically by progressive, ultimately incapacitating ataxia and pathologically by destruction of cerebellar Purkinje cells, with variable loss of other cell populations. The paraneoplastic cerebellar degeneration can antedate the recognition of malignancy and hence can be a warning sign for occult tumor. We are reporting two cases of paraneoplastic cerebellar degeneration that presented before any evidence of tumor and later developed advanced stage of malignancy not amenable for surgery.

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Author(s): Prithvi Giri, Rakesh Shukla, Vikram V Holla and Vinod Kumar Mehta

Keywords

Paraneoplastic cerebellar degeneration, Purkinje cells, Ataxia, Paraneoplastic, Paraneoplastic syndrome, Medical Case Reports

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