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Abstract
Carbapenem Resistance Enterobacteriaceae Among Wound Isolates, Kosti City, Sudan
Babiker Saad Almugadam, Abdulbagi Saeed Elbala, Abobaker Safe ELdeen Elkheir, Mohammad Abdul Mazid and Sally Adam Osman
Background: Bacterial wound infections are a major health problem worldwide and it has dangerous complications. This study aim to investigate the frequency and antibiotics susceptibility of carbapenem-resistant Enterobacteriaceae (CRE).
Methods: A total of 100 Enterobacteriaceae were isolated from patients with wound infections. Phenotypic detection of CRE was confirmed by modified Hodge test (MHT) and antibiotics susceptibility testing were performed according to clinical and laboratory standard institute (CLSI) guidelines 2011.
Results: The frequency of CRE was 6% the frequency was higher in Beta-lactam users and lower in non-Betalactam antibiotics users. In this study, most isolates are sensitive to (gentamicin 57%, meropenem 68%, and imipenem 96%) and resistant to (Ceftriaxone 100%, and Cefotaxime 79%).
Conclusion: Continuous and regular surveillance programs can aid in the development of guides for the treatment, control, and prevention of wound infections caused by carbapenem resistant Enterobacteriaceae.