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Impact of Roux-En-Y Gastric Bypass Surgery on Neurohormonal and Gastrointestinal Physiology: Insights for Future Weight Loss Efforts | OMICS International| Abstract
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
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  • Review Article   
  • J Obes Weight Loss Ther 6:356,
  • DOI: 10.4172/2165-7904.1000356

Impact of Roux-En-Y Gastric Bypass Surgery on Neurohormonal and Gastrointestinal Physiology: Insights for Future Weight Loss Efforts

Hisham Hussan1*, Emmanuel Ugbarugba2, Somashekar G Krishna3, Darwin L Conwell3, David Bradley4, Clinton K. Steven5 and Bradley Needleman6
1Obesity and Bariatric Endoscopy Section (OBES), Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Medical Center, Columbus, OH, United States
2Division of Hospital Medicine, The Ohio State University Medical Center, Columbus, OH, United States
3Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Medical Center, Columbus, OH, United States
4Division of Endocrinology, Diabetes and Metabolism, The Ohio State University Medical Center, Columbus, OH, United States
5Division of Medical Oncology, The Ohio State University, Wexner Medical Center, Columbus, OH, United States
6Center for Minimally Invasive Surgery, Department of Surgery, The Ohio State University Medical Center, Columbus, OH, United States
*Corresponding Author : Hisham Hussan, MD, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, 395 12th Ave, Suite 240 Columbus, OH 43210, United States, Tel: (614)293-6255, Fax: (614) 293-8518, Email: Hussan.Hisham@osumc.edu

Received Date: Oct 31, 2017 / Accepted Date: Nov 08, 2017 / Published Date: Nov 13, 2017

Abstract

Roux-en-Y Gastric Bypass (RYGB), is an effective weight loss intervention for patients failing conventional nonsurgical methods. Despite its popularity, only a subset of patients undergo RYGB due to its cumbersome nature. Furthermore, patients may experience nutritional deficiencies or weight regain after RYGB. This review will delineate the less known impact of RYGB on neurohormonal and gastrointestinal physiology involved in weight loss. Understanding these alterations will contribute to the development of future novel investigations targeting viable weight loss strategies.

Keywords: Obesity; Weight loss; Gastrointestinal physiology; Feeding; Neurohormonal physiology; Roux-en-Y; Gastric bypass

Citation: Hussan H, Ugbarugba E, Krishna SG, Conwell DL, Bradley D, et al. (2017) Impact of Roux-En-Y Gastric Bypass Surgery on Neurohormonal and Gastrointestinal Physiology: Insights for Future Weight Loss Efforts. J Obes Weight Loss Ther 7: 356. Doi: 10.4172/2165-7904.1000356

Copyright: © 2017 Hisham H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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