700 Journals and 15,000,000 ReadersEach Journal is getting 25,000+ Readers
This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Research Article Open Access
Potent Anti-Malaria Salts, Co-Crystals and Derivatives of Aminoquinolines with Hydroxyaromatic Acids
Antimalarial activities of salts of aminoquinolines with hydroxyaromatic acids were found to be higher than the parent components. The IC50 values of the salts were in the range of 5.9-20.3 μM against the chloroquine-resistant strain. Antimalarial actions on the parasites were found to be independent of iron chelation, inhibition of haemozoin formation, as well as independent of the anti-oxidant activity of the salts. A covalently linked amide containing compound N-(quinolin-8-yl)-2-(quinolin-8-yloxy)acetamide was identified to have potency similar to the other salts studied in the article.