alexa Abstract | Renal Cell Carcinoma Metastasis to Thyroid Gland Associated with Papillary Thyroid Carcinoma: A Case Report and Review of the Literature
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report Open Access


Metastatic thyroid gland tumor is an uncommon finding in clinical practice. We report a case of metastatic renal cell carcinoma (RCC) to the thyroid gland, associated with a Papillary Thyroid Carcinoma (PTC), in a patient who had undergone left nephrectomy for RCC 6 years earlier and operated on in our Institution for a multinodular goiter disease. Immunohistochemistry can be helpful for the differential diagnosis. Metastatic cells of RCC were positive for CD10 and vimentin and negative for thyroglobulin, calcitonin, and TTF-1. Papillary carcinoma cells were positive for Cytokeratin 19, galectin-3, CD56 and Hector Battifora Mesothelial cell monoclonal antibody-1. The association between papillary thyroid carcinoma and RCC is a rare condition and maybe must not be considered a fortuitous development of 2 different neoplasms.

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Author(s): Francesco Fiorentino, Cira Di Gioia, Giovanni Tortorelli, Mauro Filesi and Francesco Tartaglia


Renal cell carcinoma, Papillary thyroid carcinoma, Total thyroidectomy, Immunohistochemistry, Medical Case Reports

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