alexa Abstract | Role of the Mitral Valve Resistance in Evaluation of Mitral Stenosis Severity
ISSN: 2168-9784

Journal of Medical Diagnostic Methods
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Background: Mitral valve resistance (MVR) is an important hemodynamic consequence of mitral stenosis (MS). We aimed to determine whether the mitral valve resistance could be used as a clinically reliable method for estimation of MS severity.

Materials and Methods: Transthorathic echocardiographic study of 128 patients with rheumatic MS to estimate; mitral valve area (MVA); planimerty (2D) and pressure half time (PHT), mitral valve score (MVS), right ventricular systolic pressure (RVSP), mean transmitral pressure gradient (MPG), diastolic filling time (DFT), left ventricular out flow tract diameter (LVOTd) and velocity time integral (LVOT vti), MVR calculated as: MPG/aortic flow ratio [(LVOTd) (LVOTvti)/DFT] in dynes.sec.cm-5.

Results: MVR at cut off values of: ≥105.26 dynes.sec.cm-5, had a sensitivity of 86.7% and a specificity of 74.5% for severe MS, between 76.02 and 105.26 dynes.sec/cm5 it had a sensitivity of 85.2% and a specificity of 72% for moderate MS, at ≤76.02 dynes.sec/cm5 it had a sensitivity of 81% and a specificity of 91% for mild MS. MVR in moderate MS; can detect symptomatic patients at a cut off value ≥85.65 dynes.sec/cm5 with a sensitivity of 87% and a specificity of 100%. MVR had positive correlations with MVS and RVSP (r=0.618 and 0.401), -ve correlations with MVA-2D and PHT (r=-0.559 and -0.284), P<0.01. MVR was an independent predictor of the NYHA functional class (B ± SE0.003 ± 0.001, odds ratio 0.3, P<0.01). NYHA functional class showed the best correlation with MVR (r=0.630, P<0.01).

Conclusion: MVR can be used as a parameter for expression of stenosis severity, and could be used for evaluation of symptomatic moderate MS.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): El-Dosouky II, Meshrif AM

Keywords

Hemodynamics, Mitral valve stenosis, Mitral valve resistance, Differential Diagnosis, Laboratory Diagnosis, Medical Diagnosis, Retrospective Diagnosis

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords