alexa Abstract | Screening of Novel Natural Product Derived Compounds for Drug Discovery in Inflammation
ISSN: 2329-9029

Journal of Plant Biochemistry & Physiology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Natural products are often a source for bioactive compounds which have great potential for developing novel therapeutic agents. The present study was to evaluate anti-inflammatory potential of six compounds A: Raffinose, B: Sucrose, C: Benzoic acid, D: Trehalose, E: Quinic Acid and F: Ferulic acid on bacterial lipopolysaccharide (LPS) induced inflammation in RAW 264.7 macrophages by employing in vitro methods: nitric oxide (NO) and Nitro blue tetrazolium (NBT) assays. These compounds are found in many plants, including palm, date palm, pomegranate, custard apple, wood apple, water chestnut and Indian plum, among others and it has been found that many of these compounds are effective anti-inflammatory agents, with anti-oxidant activities. The study revealed that compound C exhibited maximum anti-inflammatory activity at a concentration as low as one ng/ml. Compounds A, B and E also showed anti-inflammatory activity but at a higher concentration but compound D and F did not show antiinflammatory activity.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Shinjini Mitra, Srabani Kar, Konsam Surajlata and Ena Ray Banerjee


Oxidative pathways, Therapeutic molecule, Prophylaxis, Functional food, Cell based assays, Plant Biochemistry

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version