alexa Abstract | Tolosa Hunt Syndrome: Increased Severity on Second Attack
ISSN: 2329-9126

Journal of General Practice
Open Access

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Case Report Open Access


Tolosa Hunt syndrome (THS) is a rare cause of painful ophthalmoplegia with an estimated annual incidence of 1 case per million per year. It is caused by a nonspecific inflammatory process, of unknown etiology, involving the cavernous sinus, the superior orbital fissure and/or the orbital apex. It is classically described as an episodic orbital pain associated with paralysis of one or more of the 3rd, 4th and 6th cranial nerves, resolving spontaneously or with the commencement of steroids. I report a female patient who had 2 attacks of THS separated by a period of 10 months. She presented with retro-orbital headache, exophthalmos, and ophthalmoplegia of left eye, on both attacks, and was treated with high dose prednisolone. On first attack she improved within 6 weeks of treatment. On second attack, the patient had a higher Erythrocyte sedimentation rate (ESR) and developed 2 relapses on corticosteroids tapering, requiring a prolonged course of treatment, for 27 weeks, which suggests that the disease activity may get more severe on further attacks of the disease.

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Author(s): Ali A Alzu’bi


Tolosa-Hunt syndrome, Painful ophthalmoplegia, Proptosis, Headache, Retro-orbital, Ptosis, Clinical Guidelines,Community Health Doctors,Dental Medicine,Emergency Care

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