Journal of Nanomedicine & Nanotechnology

Abstract

Iron Oxide Biomagnetic Nanoparticles (IO-BMNPs); Synthesis, Characterization and Biomedical Application–A Review

Amirsadegh Rezazadeh Nochehdehi, Thomas S, Sadri M, Afghahi SSS and Mehdi Hadavi SM

Nanotechnology is a multidisciplinary branch of science which encompasses numerous diverse fields of science and technology, ranging from biomedical, pharmaceutical, agricultural, environmental, advanced materials, chemical science, physics, electronics, information technology, and so on. Physical and Chemical properties as a major advantages of Nanoparticles can be used in various applications from Industries to medicine. Besides, Magnetic nanoparticles for medical applications have been developed by many researchers. In recent decades, it has received attention by virtue of their potential for applications in different fields. Due to several advantages and widespread applications of magnetic Nanoparticles in biotechnology, medical, material science, engineering, and environmental areas, much attention has been paid to the synthesis of different kinds of Biomagnetic nanoparticles (BMNPs). Core-shell nanoparticles include of coated various materials like: biopolymers (Chitosan, PAA) and bioceramics (Hydroxyapatite) as a shell on top of them and different hard and soft materials like metal oxide (Iron oxide and Cob alt composite) as a core. Improved properties of core-shell nanoparticles like less cytotoxicity, increase biocompatibility, decrease in an interactions with biomolecules, increase physicochemical stability and sort of that, can be due to their use in biological applications. After reviewing several research and review articles and synthesis procedure of Iron based Bio-magnetic Nanoparticles (BMNPs), we should emphasize that, It can be used in different applications like magnetic resonance imaging (MRI), drug delivery systems (DDS), immunoassay, also specially in diagnosis and treatment of cancer via hyperthermia (heat therapy) method.