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Antimicrobial chemotherapy is the clinical application of antimicrobial agents to treat diseases of infection. Three forms of antimicrobial chemotherapy: Antibacterial chemotherapy, the use of antibacterial drugs (antibiotics) to treat bacterial infection, anti-fungal chemotherapy and anti-viral chemotherapy.
Resistance may involve decreased entry of the drug, changes in the receptor (target) of the drug, or metabolic inactivation of the drug impacts antimicrobial chemotherapy. Combinations of antibiotics may act synergistically-producing an effect stronger than the sum of the effects of the two drugs alone or antagonistically, if one agent inhibits the effect of the other. Adverse Effects of Antimicrobial Agents: Many antibiotics are toxic to the host. Alterations of the normal intestinal flora caused by antibiotics may result in diarrhea or in superinfection with opportunistic pathogens.
Related Journals of Antimicrobial Chemotherapy
Chemotherapy: Open Access, Journal of Antimicrobial Chemotherapy, Antimicrobial Agents and Chemotherapy, Journal of Chemotherapy, Japanese Journal of Chemotherapy.