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Hypertrophic Cardiomyopathy (HCM) is a disease in which a portion of the myocardium (heart muscle) is hypertrophic(enlarged) without any obvious cause, creating functional impairment of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. It is the leading cause of sudden cardiac death in young athletes.