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The characteristic signs and symptoms of major depression include loss of interest in activities that were once interesting or enjoyable, including sex; loss of appetite (anorexia) with weight loss or overeating with weight gain; loss of emotional expression (flat affect); a persistently sad, anxious or empty mood.
Depression can be treated. Treatment includes medicines, talk therapy, or both. If you are thinking about suicide or are very depressed and cannot function, you may need to be treated in a hospital.