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Membrane trafficking is the process by which proteins and other macromolecules are distributed throughout the cell, and released to or internalized from the extracellular space. Membrane trafficking is essential for transport of proteins and other macromolecules to various destinations inside and outside of the cell. Membrane trafficking also helps cells to maintain cellular homeostasis, as well as to meet specific demands during signal perception and transduction. Trafficking within the network supports intercellular communication and construction of extracellular matrix through secretion, nutrient import and processing of extracellular signals through endocytosis, and periodic turnover and renewal of cellular organelles. Unfortunately, membrane trafficking also facilitates invasion of cells by pathogenic microorganisms, and trafficking defects occur in several diseases. Thus the mechanisms of membrane trafficking are central to both cellular physiology and pathology. Research in the Department of Cell Biology addresses both the physiological and pathological aspects of membrane trafficking.
Related journals of Membrane Trafficking
Journal of Clinical & Cellular Immunology, Journal of Stem Cell Research & Therapy, Cellular and Molecular Biology, Journal of Cell Science & Therapy, Cell & Developmental Biology, Journal of Membranes Science, Current Topis in Membranes, Membrane Science and Technology, Membrane Protein Transport, Molecular Membrane Biology, Biomembranes: A Multi-Volume Treatise, Advances in Cellular and Molecular Biology of Membranes and Organelles