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The cartilage breaks down and wears away, the bones rub together. This causes the pain, swelling, and stiffness of Osteoarthritis. Being overweight, Getting older joint injury, jobs that involve kneeling or squatting for more than an hour a day that involve lifting, climbing stairs, or walking increase the risk of Osteoarthritis. A genetic defect in joint cartilage playing sports that involve direct impact on the joint (football), twisting (basketball or soccer).