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International Journal of Biomedical Data Mining

ISSN: 2090-4924

International Journal of Biomedical Data Mining

Protein sequencing

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Protein sequencing

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Protein molecules are structural and functional component of a cellular environment. Estimation of the quantity of proteins has been a routine process in scientific community and academics. Sequencing of proteins unveiled the mysteries of proteins and aided in understanding the complex structural and functional phenomena of protein networks and cascading events. Several methods are used for protein sequencing which contains enzyme based methods, mass spectrometry based methods and automated sequencing methods.

Related Journals: Proteins: Structure, Function and Genetics, Protein Science, Protein Engineering, Design and Selection, Protein Journal, Protein and Cell

Protein sequencing

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  • Ensieh Shahvazian
    Resequencing of KLF14 gene in population based family study with type two diabetes
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  • Bozena Futoma-Koloch
    C3 component deposition on Salmonella O48 cells characterized by sialylated lipopolysaccharide and different pattern of outer membrane proteins
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  • Sumru Savas
    No relationship between lipoprotein-associated phospholipase A2, proinflammatory cytokines, and neopterin   in Alzheimer's disease
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  • Mapitsi S Thantsha
    In vitro antagonistic effects of Listeria adhesion protein (LAP)-expressing Lactobacillus casei against Listeria monocytogenes and Salmonella Typhimurium Copenhagen
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  • Tibor Tot
    Multiparameter characterization of breast carcinoma: subgross, microscopy, proteins, and genes
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  • Monray Edward Williams
    Molecular validation of putative antimicrobial peptides for improved Human Immunodeficiency Virus diagnostics via HIV protein p24
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  • Kuna Yellamma
    Kuna-Yellamma-Sri-Venkateswara-University-India-Evaluation-of-neuroprotective-effect-of-silk-protein
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  • Yosef Yarden
    Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
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  • Bingsong Zheng
    Identification by deep sequencing and profiling of conserved and novel hickory microRNAs involved in the graft process
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  • Shigeomi Horito
    Reconstruction of a transmembrane protein tetraspanin (CD9) into lipid bilayer by interaction of ganglioside GM3 and tetraspanin
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  • Maria A. Miteva
    In silico screening to discover inhibitors of protein-protein interactions targeting angiogenesis
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  • Konrad Sandhoff
    Lysosomal & extracellular degradation of GlcCer: Protein & lipid modifiers
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  • Zsolt Boldogkoi
    Transcription Interference Networks examined by Single Molecule Long Read Sequencing Technology
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  • David Ben-Menahem
    O-glycosylation and protein evolution: the case of the LHb to CGb development
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  • Vladimir Sulimov
    “Vladimir Sulimov-Dimonta-Ltd-and-Lomonosov-Moscow-State-University-Russia-Protein-ligand-low-energy-minima-pose-analysis-Docking-target-functions-evaluation-with-the-FLM-program”
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  • Xingmin Sun
    A chimeric protein (mTcd138) comprising the glucosyltransferase and domains of toxin B and the receptor binding domain of toxin A provides full protection against Clostridium difficile infection in mice
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  • Simon J Clark
    The role of complement factor H-like and factor H-related proteins in age-related macular degeneration
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  • Sang Ming WANG
    Genome-scale mapping promoter variation through exome sequencing
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  • Rivan Sidaly
    Hypoxia increases the expression of enamel proteins and cytokines in an ameloblast-derived cell line
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  • Frank S. Ong
    Next-generation sequencing in personalized medicine
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  • Volker Blank
    Thioredoxin-interacting (TXNIP) protein regulates the differentiation of erythroid precursors
    PPT Version | PDF Version
  • Fang-Ching Hu
    Exploring factors associated with compliance with CKD-specific low protein supplements among CKD patients
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  • Mitchell Lerner
    Scalable Production of Highly Sensitive Nanosensors Based on Graphene Functionalized with a Designed G Protein-Coupled Receptor
    PPT Version | PDF Version
  • John P Marino
    High-resolution NMR as a Structure Assessment Tool for Protein Therapeutics
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  • Petr Kolenko
    New protein constructs from KLRB1 superfamily for immunologic and structural research
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  • Yongsheng Bai
    Decoding Next Generation Sequencing Data Using Custom-Built Computational and Quantitative Methods
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  • Mirjana Menkovska
    Wheat technological quality in relation with the composition of gluten proteins-gliadins and HMW glutenins
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  • Joanna Trojanek
    Metalloproteinases and their inhibitors gene expression profiles in leukocytes of primary hypertension (PH), non-alcoholic fatty liver disease (NAFLD), and obese children
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  • Ferdinando Febbraio
    Use of EST2 from A. acidocaldarius as bioactive part in biosensors for organophosphate detection
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  • Mark D Gorrell
    The protease fibroblast activation proteinas a biomarker and therapeutic target in cancer and chronic liver injury
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  • Alireza Hadj Khodabakhshi
    Organization and analysis of large scale mutation datasets produced by next generation sequencing technologies
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  • Paloma Manea
    COMPARISON BETWEEN HS-C REACTIVE PROTEIN AND MICROALBUMINURIA LEVELS FOR THE PROGNOSIS OF RENOVASCULAR HYPERTENSION
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  • Savithiry S. Natarajan
    Application of Proteomic Tools in Assessment of Soybean Protein Variance
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  • K Srinivas
    Association analysis of Type 2 Diabetes Proteins Interaction Network
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  • Stefanie Wienkoop
    Comprehensive Protein turnover analysis of a partial 15N stable isotope metabolic labelling experiment In Planta
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  • Eugenia Pechkova
    The role of LB thin protein film in protein crystal growth by LB nanotemplate and robot
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  • Abu Salim Mustafa
    Diagnostic potential of M. tuberculosis-specific proteins and peptides
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  • Fuad Fares
    Developing long acting agonists and antagonists of glycoprotein hormones using gene fusion and gene transfer: From bench to clinics
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  • Abeer Kadry El Zohiery
    Role of bone morphogenetic protein-2 in primary Knee osteoarthritis
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  • Huseyin Cimen
    Discovery-based Targeted Proteomic Studies: Gel-based and/or off-gel protein sample preparation and purification
    PPT Version | PDF Version
  • Richard Addo
    Ocular Delivery of peptides and proteins
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  • Giuseppe Manco
    Hyperthermophilic phosphotriesterases/ lactonases: Structure, function and applications
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  • Galya Naydenova Atanasova
    Pulse pressure and apolipoprotein B/Apolipoprotein A1 in relation to the metabolic syndrome and its components
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  • Andrea Chisari
    Effect of protein malnutrition during gestation and lactation on the physiology and liver structure in adult life
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  • Govindasamy Chandramohan
    Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol induced myocardial infarction in rats
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  • Zamaneh Kassiri
    Loss of tissue inhibitor of metalloproteinase-3 (Timp3) leads to abdominal aortic aneurysm (AAA)
    | PDF Version
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