Signalling

For the survival and normal functioning of a cell and ultimately of the whole organism, conservation and protection of the native DNA sequence and structure is necessary. However, our bodies are constantly exposed to diverse types of genotoxic insults from various sources that can damage cellular DNA and threaten the survival. In order to maintain genomic integrity, eukaryotic Cells have developed intricate DNA damage sensing and repair mechanism that combats the diverse sources of DNA damage and ensures survival. The signalling responses that are triggered following DNA damage from endogenous or exogenous sources give rise to a pathway called DNA Damage Response (DDR) pathway. The DDR pathway has evolved to be a complex, yet sensitive, highly integrated and interconnected pathway. In the growing environment, they are many journals in various organisations. Only a very few journals maintain high standards in terms of the content they publish, one has to be careful while picking information as content that is not reliable and untrue can be harmful to research as well as society. Generally, journals can be rated by considering impact factor, reputation of authors, editorial board members and also in terms of the fee they charge. Only high indexing journals have quality articles. Molecular Biology is one of the best journals which publish quality articles. Molecular Biology is a wide range of area that deals with different aspects. It publishes original research, review, short communication, case report, mini review etc.

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Last date updated on April, 2024