Anaphylaxis is a severe, potentially life-threatening allergic reaction. It can occur within seconds or minutes of exposure to something you're allergic to, such as a peanut or the venom from a bee sting. Anaphylaxis requires immediate medical treatment, including an injection of epinephrine.Symptoms of Anaphylaxis occur within minutes or hours as soon as exposed to allergen. The early symptoms may be mild, such as a runny nose, and nausea and vomiting. Common causing agents are venom from insect bites or stings, foods and medication. Many foods can trigger anaphylaxis ingestion of or exposure to peanuts, wheat, nuts, and certain types of seafood like shellfish, milk, and eggs are the most prevalent causes.
Anaphylaxis is a serious allergic reaction affecting many systems of the body. It is caused majorly due to the release of inflammatory mediators and cytokines from mast cells and basophils, typically due to an immunologic reaction but sometimes non-immunologic mechanism.Anaphylaxis is diagnosed on the basis of its symptoms. People with a history of allergic reactions may be at greater risk for developing a severe reaction in the future. Allergists have expertise to review the history of allergic reactions conducts diagnostic tests (such as skin-prick tests, blood tests and oral food challenges) to determine the factors and suggesting the treatment accordingly.
An anaphylactic attack can be treated immediately with an injection of epinephrine, Oxygen, Intravenous (IV) antihistamines and cortisone or beta-agonist. At risk of anaphylaxis, carry auto injectable epinephrine (adrenaline). This is a single dose of medication that is injected into the thigh during an anaphylactic emergency. The best ways to manage condition are avoid allergens that trigger your allergic reactions.In Singapore the mortality rate for anaphylaxis is approximately about 4-5 percent of the population.