Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest and can lead to a variety of emotional and physical problems. Symptoms of depression are Feelings of sadness, emptiness, angry outbursts, Sleep disturbances, Changes in appetite, Anxiety, Trouble thinking, making decisions etc.
Annual prevalence rates range from 0.80-5.8% whereas lifetime prevalence rates range from 1.5-16.4%. In Singapore it is about 5%. Women have a relatively higher rate of occurrence of depression than men. The sex ratio is 2:1.
To diagnosis Depression various tests like Physical test, Lab tests, Psychological test, Diagnostic and Statistical Manual of Mental Disorders (DSM-5) can be conducted. Medications and psychological counseling (psychotherapy) are very effective for most people with depression. Selective serotonin reuptake inhibitors (SSRIs), Serotonin-norepinephrine reuptake inhibitors (SNRIs), Norepinephrine-dopamine reuptake inhibitors (NDRIs), Atypical antidepressants etc. antidepressant drugs can be used.
Many scientists in USA doing research on depression and thyroid function abnormal thyroid function may be associated with depression. Researchers at the Singapore general hospital are looking for volunteers to participate in a research to evaluate the role of thyroid function in depression.