Paget’s disease of bone is a chronic disease of the skeleton. Normally it grows on the bone and makes the bone breaks or bones can grow larger than before. Bone consists of osteoblasts, Osteoclasts, Ostecytes, Matrix. All patients who were evaluated and treated for EMPD at the Singapore NCC from January 2003 to December 2011 were included in this study.
Information regarding the patients’ demographics, age at diagnosis, presenting symptoms, disease sites and presence of synchronous lesions, evaluations, definitive treatments, post-operative adjuvant therapies, follow-up periods, survival periods, complications, recurrences, and deaths were collected. Chondrosarcoma is the most frequently occurring bone sarcomas of adulthood. The incidence is about 0.2/100 000 per year, with the most common age at diagnosis being between 40 and 70 years and the male–female ratio is ∼2.5.
Although initially diagnosed by a primary care physician, Endocrinologists (inward medication doctors who have some expertise in hormonal and metabolic issue), rheumatologists (inside pharmaceutical doctors who represent considerable authority in joint and muscle issue), orthopaedic specialists, neurosurgeons, neurologists, oral and maxillofacial specialists, podiatrists, and otolaryngologists are by and large learned about treating Paget's malady, and may be called upon to assess particular indications. The goal of treatment is to relieve bone pain and prevent the progression of the disease.