Sarcoidosis is a systemic granulomatous disorder of unknown cause characterised by frequent pulmonary involvement. The disease occurs throughout the world, affecting both sexes, and all races and ages.
Sarcoidosis can affect any organ, although the lungs are involved in up to 95% of patients. Other organ systems commonly affected include the skin, eyes, and lymphoreticular system. Estimates of organ involvement are confounded by the method of discovery, referral bias, and the sensitivity of diagnostic modalities.
The estimated annual incidence of sarcoidosis in Singapore was 0.56 per 100,000.Overall mean spirometry was unimpaired and prognosis was good with 79.2% showing no radiological deterioration. There were no significant differences in organ involvement or treatment between ethnic groups.