Toxocariasis is caused by infestation of the larvae of two widespread roundworms, Toxocara canis and Toxocara cati. Dog and cat intestines are the reservoir for T. canis and T. cati respectively. T. canis is more commonly responsible for human disease. Human toxocariasis is widespread and is usually symptom-free.Human toxocariasis is a parasitic zoonosis caused primarily by Toxocara canis and Toxocara cati, which are intestinal roundworms of canids and felids of worldwide occurrence. Transmission is fecal-oral, and infections in human hosts can occur upon accidental ingestion of embryonated eggs as a cause of geophagia, poor hygiene, contact with dogs and cats.
Asymptomatic patients and patients with mild symptoms do not require anthelminthic therapy because infection is usually self-limited. For patients with moderate to severe symptoms, mebendazole 100 to 200 mg po bid for 5 days or albendazole 400 mg po bid for 5 days is often used, but the optimal duration of therapy has not been determined.In the Singapore, about 160 cases of Toxocara infection are reported in humans each year. Almost 8 % of the Singapore population is infected with Toxocara.