A temporary short-term memory loss followed by full recovery. The disorder tends to affect middle-aged adults and may be attributed to cerebral ischemia. It is usually not accompanied by other mental deficiencies. • Yamane et al reported rather diffuse cerebral hypoperfusion on SPECT that improved months later upon repeating the test in a patient with TGA. Yang et al also reported hypoperfusion in the cerebellar vermis that recovered by the time of follow-up examination.
In women, episodes may be more associated with emotional precipitating events, a history of anxiety, or pathological personality. Conditions predisposing to this scenario might include venous anatomy anomalies, integrity of jugular vein valves, timing of the trigger, and severity of the inciting event. In support of the above concept of venous congestion are Schreiber et al's finding of a higher prevalence of internal jugular veinvalve incompetence in patients with TGA versus normal controls and Cejas et al's similar findings.