Tuberculosis (TB) in the past also called phthisis, phthisis pulmonalis, or consumption, is a widespread, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis.
Singapore is a nation where the cases of incident TB are inreasing constantly from 2011 to 2013. in 2011 the rate of TB incidence was 41 and it raised to 47 in 2013.
Treatment of TB uses antibiotics to kill the bacteria. Effective TB treatment is difficult, due to the unusual structure and chemical composition of the mycobacterial cell wall.
The BCG vaccine has limitations, and research to develop new TB vaccines is ongoing. A number of potential candidates are currently in phase I and II clinical trials.