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Type 1 diabetes usually develops as a result of autoimmune pancreatic beta-cell destruction in genetically susceptible individuals. Up to 90% of patients will have autoantibodies to at least one of 3 antigens: glutamic acid decarboxylase (GAD); insulin; and a tyrosine-phosphatase-like molecule, islet auto-antigen-2 (IA-2). Diabetes mellitus has been on the rise in Singapore.
The incidence of Type 1 diabetes in childhood is 2.46 per 100000 children 0-12 years of age Singapore has one of the world's fastest ageing populations, and even now, 32.4% of Singaporeans 60-69 years of age have diabetes. There's no cure for diabetes, so treatment aims to keep your blood glucose levels as normal as possible and to control your symptoms to prevent health problems developing later in life.
The European Commission Directorate General for Research and Innovation (DG RTD) and the JDRF (formerly Juvenile Diabetes Research Foundation) jointly organized a workshop held in Brussels on type 1 diabetes with the ultimate goal of defining the state-of-art in the field, identifying gaps, and brainstorming about the possibilities offered by personalized medicine approaches in this area. The speakers laid out that time frame for the next major advances in type 1 diabetes
