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Pathophysiology
A bleeding disorder is a health problem that makes it hard for a person to stop bleeding. Normally when a person is hurt, a clot forms to stop the bleeding quickly. This clotting process, called coagulation (koh-ag-yuh-LAY-shuhn), changes blood from a liquid to a solid state. For blood to clot, your body needs a type of blood cell called platelets. Your body also needs blood proteins called clotting factors.
Statistics on Women's bleeding disorders in United Kingdom
Research shows that 10-30 percent of women with heavy periods have a bleeding disorder, usually VWD. In other cases, heavy periods may be caused by: · Hormonal changes · Diseases or disorders of the reproductive system · Use of an intrauterine (IN-truh-YOO-tur-in) device (IUD) for birth control · Use of some medicines.
Treatment of Women's bleeding disorders
Although bleeding disorders cannot be cured, medicine can control the symptoms. Treatment for bleeding disorders varies. Most women with VWD don't need to take medicine. People with mild bleeding problems may only need treatment before or after surgery and dental work or after an injury. More severe symptoms can be controlled with daily medicines.
Major research on Women's bleeding disorders in United Kingdom
Several bleeding disorders are associated with normal routine initial hematologic laboratory studies (ie, platelet count, PT, aPTT, and PFA-100). In some cases, the sensitivity of these studies for detecting certain conditions, such as some types of VWD or milder factor deficiencies, may be limited. In other cases, neither fibrin generation nor platelet function is impaired; therefore, coagulation studies and quantitative and qualitative platelet test results are normal.
