Smallpox

The classical form of smallpox caused by variola has been divided into five major clinical types by world health organization (WHO): 1. Ordinary smallpox that occurs in 90% of cases with a case-fatality rate ranging from 10–75% correlated with the severity of rash. 2. Modified smallpox, that occurs in 5% of cases with a case-fatality rate near 10%, less severe in its clinical presentation and frequent among previously vaccinated individuals; 3. Flat smallpox, that occurs in 5% of cases with a case-fatality rate above 80%, distinguished by a more slowly developing rash and generalized infection; 4. Haemorrhagic smallpox, that occurs in 1% of cases with casefatality rate of 100%, characterized by haemorrhages into the skin and mucous membranes; 5. Variola sine eruption, that presents as a fever without rash; thus, serological evidence is required to confirm VARV infection. (Smallpox: New Perspectives Regarding Risk Assessment & Management- Jan-Cedric Hansen) Open access is the free access to scientific literature online without any restrictions on use; the open access enables better management and assessment of research and moves research along faster with greater visibility. OMICS is an example is such open access group with 700+ peer-reviewed journals on its account; the OMICS group is one of the leading Open Access Publishers which is publishing more than 1000 articles every month with the support of 50,000+ editorial board members as editorial team and aimed to disseminate the scholarly knowledge to the scientific society.

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Last date updated on April, 2024