Acne occurs most commonly during adolescence, affecting an estimated 80–90% of teenagers in the Western world. Lower rates are reported in some rural societies. In 2010, acne was estimated to affect 650 million people globally making it the 8th most common disease worldwide.
There is some low-quality evidence from single trials that LGLD, tea tree oil, and bee venom may reduce total skin lesions in acne vulgaris, but there is a lack of evidence from the current review to support the use of other CAMs, such as herbal medicine, acupuncture, or wet-cupping therapy, for the treatment of this condition. Body mass index is negatively associated with acne lesion counts in Taiwanese women with post-adolescent acne.
Overall incidence of acne is similar in both men and women, and peaks at 17 years of age. The number of adults with acne, including people over 25 years, is increasing; the reasons for which are unclear.