Intussusception is a serious disorder in which part of the intestine slides into an adjacent part of the intestine. This "telescoping" often blocks food or fluid from passing through. Intussusception also cuts off the blood supply to the part of the intestine that's affected. Intussusception can lead to a tear in the bowel (perforation), infection and death of bowel tissue. Intussusception is the most common cause of intestinal obstruction in children younger than 3.
Studies have shown high intussusception rates in Spain,a hospital-based retrospective observational study of the intussusception risk following rotavirus vaccinations among infants in Valencia, a region of Spain with an annual birth cohort of approximately 48,000 children, during 2007–2011, using a self-controlled case series design. We performed medical record review of all cases using Brighton Collaboration´s case definition and assessed the positive predictive value (PPV) of the intussusception diagnosis code. Among 151 hospitalized cases discharged as intussusception, we confirmed 136 as Brighton Collaboration's Levels 1 or 2, resulting in a PPV of 93% (95% CI: 87%–96%). Three confirmed cases occurred within days 1–7 following the first rotavirus vaccination. The incidence rate ratio was 9.0 (95% CI: 0.9–86.5) (crude) and 4.7 (95% CI:0.3–74.1)(age adjusted)
An enema is the first step in treatment. In fact, an enema that is used to diagnose intussusception may also help to treat it. Pressure from the air or fluid may cause the intestine to correct itself. The result of an enema treatment might not last, so patients usually stay in the hospital overnight for observation. Surgery is another treatment option. Intussusception surgery involves either a large incision or a small incision and a camera. This is called laparoscopic surgery. The type of surgery depends on the location and severity of the obstruction. Intussusception surgery may include removal of the affected section of intestine.