Odontogenic tumors (OTs) are rare entities that originate in the odontogenic epithelium and ectomesenchymal tissues, which are parts of the tooth-forming apparatus. These tumors constitute a heterogeneous group of diseases with diverse clinical and histopathological features. Odontogenic tumors were 4.76% of all biopsied lesions. The mean age was 30.7 years, 57% of the patients were male. The keratocystic odontogenic tumor was the most prevalent histological type (30%), followed by the ameloblastoma (23,7%). The rate of asymptomatic cases was 75.7% in Spain.
These infections are typically polymicrobial, and anaerobic bacteria are thought to play a central etiologic role. Antibiotics are an important component in the treatment of odontogenic infections. The drugs most frequently recommended are penicillin (PEN), amoxicillin-clavulanic acid (AMC), and clindamycin (CLI)—despite reports of substantial resistance to CLI among oral pathogens. Researcxh focusing on the Expression of the transcription factor PITX2 in ameloblastic carcinoma, Primordial odontogenic tumour: clinicopathological analysis of six cases of a previously undescribed entity.