alexa Pulmonary fibrosis | Spain | PDF | PPT| Case Reports | Symptoms | Treatment

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Pulmonary Fibrosis

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  • Pulmonary fibrosis

    Pulmonary fibrosis is a condition that causes lung scarring and stiffness. It develops when the alveoli, tiny air sacs that transfer oxygen to the blood, become damaged and inflamed. Body tries to heal the damage with scars, but these scars collapse the alveoli and make the lungs less elastic. Changes in the lungs can also increase the blood pressure in the pulmonary artery.

  • Pulmonary fibrosis

    Statistical analysis on pulmonary fibrosis in Spain got the result as increased FAK expression and activity are upregulated in fibroblast foci and remodeled vessels in lung fibrosis patients. Pharmacological or siRNA-mediated targeting of FAK resulted in marked abrogation of bleomycin-induced lung fibrosis. Loss of FAK impaired the acquisition of a profibrotic phenotype in response to ET-1.

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