Rat-bite Fever | Spain| PDF | PPT| Case Reports | Symptoms | Treatment

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Rat-bite Fever

  • Rat-bite Fever
    Rat bite fever is an acute, rare disease caused by Streptobacillus moniliformis and Spirillum minus. Rats are carriers (the reservoir) of both bacteria but rarely show signs of illness. Disease has been reported in mice, birds, guinea pigs, and nonhuman primates. The majority of cases are due to the animal's bite. It can also be transmitted throughout food or water that is contaminated with rat feces or urine. Both the spirillary and streptobacillary forms affect mainly people who live in cities in crowded conditions, as well as biomedical laboratory personnel. In America and Europe, rat bite fever is usually due to S. moniliformus, while in Asia it is usually due to S. minus.
  • Rat-bite Fever

    The disease is most often seen in Asia, Europe, North America. It is transmitted to people in around 10% of rat bites. Symptoms of the streptobacillary form include recurrent fever, rash, and arthralgias. The spirillary form causes relapsing fever, rash, and regional lymphadenitis. Treatment of RBF includes administration of amoxicillin 1 g per oral, procaine penicillin G 600,000 units IM every 12 hours, or penicillin V 500 milligrams per oral for 7 to 10 days. Erythromycin might be administered to people who are allergic to penicillin. Doxycycline 100 milligrams every 12 hours for 14 days is an alternative form of treatment.

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