Stuttering is an interruption of the normal flow of speech, which takes on many different patterns. Commonly, it involves either saying a string of repeated sounds or making abnormal pauses during speech. In early childhood, stuttering is sometimes part of normal speech development. In fact, about 5% of all young children go through a brief period of stuttering when they are learning to talk. Stuttering typically is first noticed between the ages of 2 and 5. It usually goes away on its own within a matter of months. In a small number of children (around 1%), stuttering continues and may get worse.
In addition, normal problems with fluency tend to come and go, or happen only at certain times (such as when a child is tired or excited), but true stuttering is present most of the time. Once a child begins to stutter, he or she may feel embarrassed, self-conscious or anxious when asked to speak. The child may find it hard to socialize with friends and also may intentionally avoid situations where talking is expected, such as telephone calls, classroom discussions and school plays. Somewhat unexpectedly, many children who stutter have no problem when they sing. According to some experts, this is because speaking and singing often come from opposite sides of the brain, especially in right-handed people.
Temporal trends of serotypes from invasive pneumococcal disease (IPD) in Spain from 1979 to September 2007 under antibiotic and vaccine pressure were analyzed. A significant trend in pneumococcal conjugate 7-valent vaccine (PCV7) serotypes (except serotype 4) was found, whereby the prevalence increased from the early 1980s and decreased in the 2000s for all but serotype 23F, which began decreasing in the late 1980s. Among the major non-PCV7 serotypes, a significant decrease was observed for serotypes 1, 5, and 7F in the 1980s.