Major research on Trichomoniasis was done, The Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model.Tritrichomonas foetus: budding from multinucleated pseudocysts.Immunological and biochemical analysis of glycosylated surface antigens and lipophosphoglycan of Tritrichomonas foetus.Degradation of bovine complement C3 by trichomonad extracellular proteinase.Conservation of a protective surface antigen of Tritrichomonas foetus.
Trichomoniasis is a sexually-transmitted disease associated with urethritis, vaginitis, cervicitis, pelvic inflammatory disease, and tubal infertility, and it is also linked to cervical cancer. Up to 10 to 50% of infected women are asymptomatic and 50% of these women will develop clinical symptoms during the subsequent 6 months. Moreover, reinfection may occur by sexual contact with the man who acts as an asymptomatic carrier.
The effectiveness of metronidazole (Flagyl) and nimorazole (Naxogin) has been compared by using these drugs in the recommended dosage in alternate patients in a series of 218 consecutive cases of vaginal trichomoniasis. Follow-up tests in 100 patients treated with metronidazole and 97 treated with nimorazole indicated cure-rates of 95 and 82 per cent. respectively. The extrapolated statistics of prevalence of Trichomoniasis are 30,135,354 of total population.