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Ureteral Obstruction

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  • Ureteral Obstruction

    Pathophysiology

    Ureteral Obstruction is structural or functional hindrance of normal urine flow, sometimes leading to renal dysfunction (obstructive nephropathy). Ureteral obstruction can be classified as intraluminal or extraluminal. Intraluminal causes include kidney stones, blood clots and scarring; these conditions usually cause unilateral obstruction and Extraluminal causes include several conditions related to enlarged masses that place pressure on the ureter and create obstruction.

  • Ureteral Obstruction

    Disease statistics

    The frequency of CAUTI in patients who underwent routine catheter changes was 30% as compared to 86% among patients undergoing PRN catheter changes for obstruction only. These differences did not reach statistical significance.

  • Ureteral Obstruction

    Disease treatment

    Stents or drains placed in the ureter or in a part of the kidney called the renal pelvis may provide short-term relief of symptoms. Long-term relief from obstructive uropathy requires surgery. A Foley catheter, placed through the urethra into the bladder, may also be helpful.

  • Ureteral Obstruction

    Major research

    Several studies have shown that unilateral ureteral obstruction is accompanied by complex changes in renovascular response and function during the first 24 hours of its course. The increase in sensitivity to angiotensin II conduces to progressive vasoconstriction in cortex and medulla after 2 hours of obstruction.

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