Pathophysiology: Viral hemorrhagic fever (VHFs) is a general term to severe group of illness caused by RNA viruses from several viral families. It is a severe multisystem syndrome caused by infectious viruses which lead to a potentially lethal disease syndrome characterized by fever, malaise, vomiting, mucosal and gastrointestinal (GI) bleeding.VHF is caused by viruses of four families: arenaviruses, filoviruses, bunyaviruses, and flaviviruses.
Disease Statistics: Although Spain is one of the most industrialized nations of the world, Ebola has also been reported frequently. In 2011, the existence of Crimean-Congo Hemorrhagic fever (CCHF) was also found in ticks, indicating the potential risk of transmission to people. It is commonly spread by the Hyalomma tick.
Treatment: Patients usually receive supportive therapy but as such there are no other treatment or established cure for VHFs. Ribavirin, an anti-viral drug, have been effective in treating some individuals with Lassa fever or HFRS. Treatment with convalescent-phase plasma has been used with success in some patients with Argentine hemorrhagic fever.
Research: There are several major research institutes woriking for viral hemorrhagic fever in Spain. Researchers from La Rioja and some major hospitals are primarily involved in the above study of viral hemoharrgic fever.