Alaa El-Din Hamid Sayed

Alaa El-Din Hamid Sayed

Assiut University, Egypt

Title: γ-Irradiation induced erythrocytes malformations of medaka (Oryzias latipes)


Alaa El-Din Hamid Seyed Ali is a lecturer at Department of Zoology , Faculty of Science,ِAssiut University. He completed his Ph. D. In Zoology ( Fish Biology ) , Faculty of Science, Assiut University, 2011. He has published more than 20 research papers and reviewer of International Journal of Fisheries and Aquaculture, International Journal of Biochemistry and Biotechnology and Journal of Toxicology and Environmental Health Sciences.His research interest is the study of the effects of pollution (Air, chemical and water) and it's toxicity on fish.


The previous studies indicated the dangerous effects γ-irradiation on one of the most economically important Japanese fishes namely, Medaka (Oryzias latipes). In the present work, erythrocytes alterations were recorded as hematological bioindicators for γ-Irradiation. After exposure of medaka fish to two different doses of γ-radiation (2Gy and 10 Gy) many red blood cells malformations were recorded in γ-Irradiated fishes in comparison with control fishes. Those malformations as acanthocytes (Ac), crenated cells (Cr), rupture of cell membrane, Amoeboid RBCs shaped, sickle cells and drop like tail in some RBCs. Also, the frequencies of those malformations were increased with γ-irradiation dose. No micronuclei were reported in all groups but nuclear abnormalities were observed. It was concluded that, the γ-Irradiation caused erythrocytes malformations in shape and number indicated its dangerous effects on medaka fish.

Keywords: γ-irradiation, erythrocytes, Micronucleus, Oryzias latipes