Ivan H El-Sayed

Ivan H El-Sayed

University of California, USA

Title: Endoscopic surgery of the skull base and paranasal sinuses


Dr. El-Sayed completed his Otolaryngology training at Boston University and a Head and Neck Surgical Oncology fellowship at the University of California San Francisco in 2003. He is currently the Co-Director of the Center of Minimally Invasive Skull Base Surgery at UCSF and focuses on management of tumors of the paranasal sinuses, skull base, salivary glands and infratemporal fossa. His research interests are endoscopic skull base surgery and also nanotechnology in head and neck cancer as the Director of the Head and Neck Nanomedicine Laboratory. His team has put on an annual course “Surgical Approaches to the Skull Base” for neurosurgical and otolaryngology residents for the past 3 years. Dr. El-Sayed has authored nearly 50 journal articles or book chapters, including the number 1 cited article in the fi eld of chemistry in 2007. He is serving or has served on the editorial boards of the World Journal of Oncology, Journal of Nanomedicine & Nanotechnology, Otolaryngology-Omics Group, ISRN Nanotechnology- Hindawi, and the World Journal of Otolaryngology, and the Open Otorhinolaryngology Journal.


Since Ketcham’s landmark article on craniofacial resection in 1963 the fi eld of skull base surgery has generated signifi cant controversy. It took nearly 40 years to produce convincing data regarding safety and outcomes of open craniofacial resection or malignant disease. Over the past decade there has been a revolution in the management of paranasal sinus tumors with or without skull base involvement with introduction of endoscopic technology and expanded endonasal corridors allows surgical approach to lesions of the a paranasal sinuses, infratemporal fossa, anterior cranial fossa, sellar/suprasellar/infrasellar lesions, and the crainiocervical junction. Using a corridor concept to approach tumors, two surgeons can work with a four handed approach to dissect tumors while maintaining control of the surgical fi eld. Th e proposed benefi ts of these techniques include improved cosmesis and potentially less morbid procedures due to reduced brain retraction, blood loss, and a smaller wound. Critics of these techniques question the ability to achieve surgical margins, the use of piecemeal tumor resection, and the outcomes of these procedures. Th is talk will investigate these issues and the status of Expanded Endonasal Surgery in 2012 based on the literature and the authors personal experience at UCSF incorporating endoscopic skull base approaches into the management of these lesion.